SKYGLO: Glofitamab in Combination With Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Pola-R-CHP in Previously Untreated Patients with Large B-Cell Lymphoma

Condition: Diffuse Large B-Cell Lymphoma

Sponsor: Hoffmann-La Roche

<b>Full Title</b><br> Protocol GO44145: A Phase III, Multicenter, Randomized, Open-Label Study Comparing the Efficacy and Safety of Glofitamab (RO7082859) in Combination With Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Pola-R-CHP in Previously Untreated Patients with Large B-Cell Lymphoma <br><br> <b>Study Treatment</b><br> CD20xCD3 bispecific antibody glofitamab in combination with Pola-R-CHP vs Pola-R-CHP alone <br><br> <b>Eligibility/Info</b><br> Untreated CD20-positive Large B-Cell Lymphoma of one of the following types:<br> &nbsp &nbsp &nbsp - DLBCL, not otherwise specified (NOS) including germinal centre B-cell type, activated B-cell type<br> &nbsp &nbsp &nbsp - T-cell/histiocyte-rich large B-cell lymphoma<br> &nbsp &nbsp &nbsp - Epstein-Barr virus-positive DLBCL, NOS<br> &nbsp &nbsp &nbsp - Kaposi’s sarcoma-associated herpesvirus/human herpesvirus-8 positive DLBCL<br> &nbsp &nbsp &nbsp - DLBCL/HGBCL with MYC and BCL2 rearrangements<br> &nbsp &nbsp &nbsp - HGBCL, NOS <br><br> <b>Contact</b><br> For more information you may contact the Research Department through the NYCBS HALO Messaging Center or call directly: <a href="tel:631-675-5075">631-675-5075</a>. <br><br> <b>Locations</b><br> <a href="https://nycancer.com/locations/Babylon_Medical_Oncology">Babylon Medical Oncology</a><br> <a href="https://nycancer.com/locations/central_park_medical_oncology">Central Park Medical Oncology</a><br> <a href="https://nycancer.com/locations/eastchestercancercenter">Eastchester Cancer Center</a><br> <a href="https://nycancer.com/locations/lake_success_medical_oncology">Lake Success Medical Oncology</a><br> <a href="https://nycancer.com/locations/Patchogue_Medical_Oncology">Patchogue Medical Oncology</a><br> <a href="https://nycancer.com/locations/Port_Jefferson_Medical_Oncology">Port Jefferson Medical Oncology</a><br> <a href="https://nycancer.com/locations/Port_Jefferson_Station_Medical_Oncology">Port Jefferson Station Medical Oncology</a><br> <a href="https://nycancer.com/locations/Riverhead_Medical_Oncology">Riverhead Medical Oncology</a><br>

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