<b>Full Title</b><br> BC-IMT-04: Randomized, Open-label Study of the Bria-IMT Regimen and Check Point Inhibitor vs Physician’s Choice in Advanced Metastatic Breast Cancer <br><br> <b>Study Treatment</b><br> GM-CSF-secreting breast cancer vaccine SV-BR-1-GM in combination with anti-PD1 immunotherapy retifanlimab-dlwr <br><br> <b>Eligibility/Info</b><br> Eligible patients will have one of the following prior treatment histories: <br> - <u>HR+/HER2-</u>: Previously treated with at least 2 prior chemotherapy or targeted therapy regimens<br> - <u>HER2+</u>: Previously treated with at least 3 treatment regimens including 2 anti-HER2 therapies<br> - <u>TNBC</u>: Exhausted all standard of care therapies known to confer clinical benefit<br> - <u>HER2-Low</u>: Previously treated with at least 1 anti-HER2 therapy in addition to the appropriate HR status therapies<br> - <u>Actionable Mutation</u>: Patients with an actionable mutation must have been treated with appropriate targeted therapy <br><br> <b>Contact</b><br> For more information you may contact the Research Department through the NYCBS HALO Messaging Center or call directly: <a href="tel:631-675-5075">631-675-5075</a>. <br><br> <b>Locations</b><br> <a href="https://nycancer.com/locations/Babylon_Medical_Oncology">Babylon Medical Oncology</a><br> <a href="https://nycancer.com/locations/central_park_medical_oncology">Central Park Medical Oncology</a><br> <a href="https://nycancer.com/locations/eastchestercancercenter">Eastchester Cancer Center</a><br> <a href="https://nycancer.com/locations/lake_success_medical_oncology">Lake Success Medical Oncology</a><br> <a href="https://nycancer.com/locations/Patchogue_Medical_Oncology">Patchogue Medical Oncology</a><br> <a href="https://nycancer.com/locations/Port_Jefferson_Medical_Oncology">Port Jefferson Medical Oncology</a><br> <a href="https://nycancer.com/locations/Port_Jefferson_Station_Medical_Oncology">Port Jefferson Station Medical Oncology</a><br> <a href="https://nycancer.com/locations/Riverhead_Medical_Oncology">Riverhead Medical Oncology</a><br>